Liver cancer stem cell dissemination and metastasis: uncovering the role of NRCAM in hepatocellular carcinoma

Liver cancer stem cell dissemination and metastasis: uncovering the role of NRCAM in hepatocellular carcinoma

Abstract Background Liver cancer stem cells (LCSCs) play an important role in hepatocellular carcinoma (HCC), but the mechanisms that link LCSCs to HCC metastasis remain largely unknown. This study aims to reveal the contributions of NRCAM to LCSC function and HCC metastasis, and further explore its...

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Bibliographic Details
Main Authors: Lingyun Zhou, Linye He, Chang-Hai Liu, Huandi Qiu, Li Zheng, Klarke Michael Sample, Qin Wu, Jiaxin Li, Kunlin Xie, Javier Ampuero, Zhihui Li, Duoduo Lv, Miao Liu, Manuel Romero-Gómez, Yiguo Hu, Hong Tang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Liver cancer stem cells (LCSCs)
Hepatocellular carcinoma (HCC)
Metastasis
NRCAM
Single-cell RNA sequencing
Epithelial-mesenchymal transition (EMT)
Online Access:https://doi.org/10.1186/s13046-023-02893-w

Internet

https://doi.org/10.1186/s13046-023-02893-w

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