Toll-Like Receptor-Induced Immune Responses During Early Childhood and Their Associations With Clinical Outcomes Following Acute Illness Among Infants in Sub-Saharan Africa

Toll-Like Receptor-Induced Immune Responses During Early Childhood and Their Associations With Clinical Outcomes Following Acute Illness Among Infants in Sub-Saharan Africa

Severely ill children in low- and middle-income countries (LMICs) experience high rates of mortality from a broad range of infectious diseases, with the risk of infection-related death compounded by co-existing undernutrition. How undernutrition and acute illness impact immune responses in young chi...

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Bibliographic Details
Main Authors: Luke S. Uebelhoer, Agnes Gwela, Bonnie Thiel, Sophie Nalukwago, John Mukisa, Christopher Lwanga, Justine Getonto, Emily Nyatichi, Grace Dena, Alexander Makazi, Shalton Mwaringa, Ezekiel Mupere, James A. Berkley, Christina L. Lancioni
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
sepsis
toll-like receptor
lipopolysaccharide
malnutrition
pediatric
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.748996/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.748996/full

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