Alcohol consumption, depression, overweight and cortisol levels as determining factors for NR3C1 gene methylation

Alcohol consumption, depression, overweight and cortisol levels as determining factors for NR3C1 gene methylation

Abstract The NR3C1 glucocorticoid receptor (GR) gene is a component of the stress response system, which can be regulated by epigenetic mechanisms. NR3C1 methylation has been associated with trauma and mental issues, including depression, post-traumatic stress, anxiety, and personality disorders. Pr...

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Bibliographic Details
Main Authors: Júlia de Assis Pinheiro, Flávia Vitorino Freitas, Aline Ribeiro Borçoi, Suzanny Oliveira Mendes, Catarine Lima Conti, Juliana Krüger Arpini, Tamires dos Santos Vieira, Rafael Assis de Souza, Dirceu Pereira dos Santos, Wagner Miranda Barbosa, Anderson Barros Archanjo, Mayara Mota de Oliveira, Joaquim Gasparini dos Santos, Bruna Pereira Sorroche, José Claudio Casali-da-Rocha, Leonardo Oliveira Trivilin, Elizeu Batista Borloti, Iuri Drumond Louro, Lidia Maria Rebolho Batista Arantes, Adriana Madeira Alvares-da-Silva
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86189-z

Internet

https://doi.org/10.1038/s41598-021-86189-z

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