Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro

Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro

Breast tumour kinase (Brk/PTK6) is overexpressed in up to 86% of breast cancers and is associated with poorer patient outcomes. It is considered a potential therapeutic target in breast cancer, even though the full spectrum of its kinase activity is not known. This study investigated the role of the...

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Bibliographic Details
Main Authors: Rajpal S. Burmi, Gary M. Box, Umar Wazir, Haroon A. Hussain, Julie A. Davies, William J. Court, Suzanne A. Eccles, Wen G. Jiang, Kefah Mokbel, Amanda J. Harvey
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Genes
Subjects:
Brk/PTK6
ALT-PTK6
breast cancer
chemotherapy
kinase
prognosis
Online Access:https://www.mdpi.com/2073-4425/13/3/402

Internet

https://www.mdpi.com/2073-4425/13/3/402

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