Molecular evolutionary consequences of niche restriction in Francisella tularensis, a facultative intracellular pathogen.

Francisella tularensis is a potent mammalian pathogen well adapted to intracellular habitats, whereas F. novicida and F. philomiragia are less virulent in mammals and appear to have less specialized lifecycles. We explored adaptations within the genus that may be linked to increased host association...

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Bibliographic Details
Main Authors: Pär Larsson, Daniel Elfsmark, Kerstin Svensson, Per Wikström, Mats Forsman, Thomas Brettin, Paul Keim, Anders Johansson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2688086?pdf=render