Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis

Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis

Cellular effects of ionizing radiation (IR) are of great variety and level, but they are mainly damaging since radiation can perturb all important components of the cell, from the membrane to the nucleus, due to alteration of different biological molecules ranging from lipids to proteins or DNA. Reg...

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Bibliographic Details
Main Authors: Ifigeneia V. Mavragani, Zacharenia Nikitaki, Maria P. Souli, Asef Aziz, Somaira Nowsheen, Khaled Aziz, Emmy Rogakou, Alexandros G. Georgakilas
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Cancers
Subjects:
ionizing radiation effects
DNA damage and repair
complex DNA damage
carcinogenesis
immune response
radiation therapy
Online Access:https://www.mdpi.com/2072-6694/9/7/91

Internet

https://www.mdpi.com/2072-6694/9/7/91

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