Prophylactic treatment with PEGylated bovine IFNλ3 effectively bridges the gap in vaccine-induced immunity against FMD in cattle

Prophylactic treatment with PEGylated bovine IFNλ3 effectively bridges the gap in vaccine-induced immunity against FMD in cattle

Foot-and-mouth disease (FMD) is a vesicular disease of cloven-hoofed animals with devastating economic implications. The current FMD vaccine, routinely used in enzootic countries, requires at least 7 days to induce protection. However, FMD vaccination is typically not recommended for use in non-enzo...

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Bibliographic Details
Main Authors: Sarah E. Attreed, Christina Silva, Monica Rodriguez-Calzada, Aishwarya Mogulothu, Sophia Abbott, Paul Azzinaro, Peter Canning, Lillian Skidmore, Jay Nelson, Nick Knudsen, Gisselle N. Medina, Teresa de los Santos, Fayna Díaz-San Segundo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Microbiology
Subjects:
FMDV
foot-and-mouth disease
type III interferon
IFN
IFNλ3
IL28B
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1360397/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2024.1360397/full

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