Non-muscle Myosin-II Is Required for the Generation of a Constriction Site for Subsequent Abscission

Summary: It remains unknown when, where, and how the site of abscission is generated during cytokinesis. Here, we show that the sites of constriction, i.e., the sites of future abscission, are initially formed at the ends of the intercellular bridge during early midbody stage, and that these sites a...

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Bibliographic Details
Main Authors: Kangji Wang, Carsten Wloka, Erfei Bi
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219300446