Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

Gut disorders associated to irritable bowel syndrome (IBS) are combined with anxiety and depression. Evidence suggests that microbially produced neuroactive molecules, like γ-aminobutyric acid (GABA), can modulate the gut-brain axis. Two natural strains of Lactococcus lactis and one mutant were char...

Full description

Bibliographic Details
Main Authors: Valérie Laroute, Catherine Beaufrand, Pedro Gomes, Sébastien Nouaille, Valérie Tondereau, Marie-Line Daveran-Mingot, Vassilia Theodorou, Hélène Eutamene, Muriel Mercier-Bonin, Muriel Cocaign-Bousquet
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
Lactococcus lactis
GABA delivery
GAD activity
psychological stress
visceral pain
Online Access:https://elifesciences.org/articles/77100

Internet

https://elifesciences.org/articles/77100

Similar Items