Mitochondrion-processed TERC regulates senescence without affecting telomerase activities

Mitochondrion-processed TERC regulates senescence without affecting telomerase activities

Abstract Mitochondrial dysfunctions play major roles in ageing. How mitochondrial stresses invoke downstream responses and how specificity of the signaling is achieved, however, remains unclear. We have previously discovered that the RNA component of Telomerase TERC is imported into mitochondria, pr...

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Bibliographic Details
Main Authors: Qian Zheng, Peipei Liu, Ge Gao, Jiapei Yuan, Pengfeng Wang, Jinliang Huang, Leiming Xie, Xinping Lu, Fan Di, Tanjun Tong, Jun Chen, Zhi Lu, Jisong Guan, Geng Wang
Format: Article
Language:English
Published: Oxford University Press 2019-02-01
Series:Protein & Cell
Subjects:
mitochondria
retrograde signal
nucleus
transcription regulation
non-coding RNA
telomerase
Online Access:http://link.springer.com/article/10.1007/s13238-019-0612-5

Internet

http://link.springer.com/article/10.1007/s13238-019-0612-5

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