Epstein-Barr Virus Reactivation After Paediatric Haematopoietic Stem Cell Transplantation: Risk Factors and Sensitivity Analysis of Mathematical Model

Epstein-Barr Virus Reactivation After Paediatric Haematopoietic Stem Cell Transplantation: Risk Factors and Sensitivity Analysis of Mathematical Model

Epstein-Barr virus (EBV) establishes a lifelong latent infection in healthy humans, kept under immune control by cytotoxic T cells (CTLs). Following paediatric haematopoetic stem cell transplantation (HSCT), a loss of immune surveillance leads to opportunistic outgrowth of EBV-infected cells, result...

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Bibliographic Details
Main Authors: Soumya P. Kania, Juliana M. F. Silva, Oscar J. Charles, John Booth, S. Y. Amy Cheung, James W. T. Yates, Austen Worth, Judith Breuer, Nigel Klein, Persis J. Amrolia, Paul Veys, Joseph F. Standing
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
viral reactivation
viral kinetics
paediatrics
immune reconstitution
Epstein-Barr virus
haematopoietic stem cell transplant
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.903063/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.903063/full

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