Gene Doping with Peroxisome-Proliferator-Activated Receptor Beta/Delta Agonists Alters Immunity but Exercise Training Mitigates the Detection of Effects in Blood Samples

Gene Doping with Peroxisome-Proliferator-Activated Receptor Beta/Delta Agonists Alters Immunity but Exercise Training Mitigates the Detection of Effects in Blood Samples

Synthetic ligands of peroxisome-proliferator-activated receptor beta/delta (PPARβ/δ) are being used as performance-enhancing drugs by athletes. Since we previously showed that PPARβ/δ activation affects T cell biology, we wanted to investigate whether a specific blood T cell signature could be emplo...

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Bibliographic Details
Main Authors: Brigitte Sibille, Isabelle Mothe-Satney, Gwenaëlle Le Menn, Doriane Lepouse, Sébastien Le Garf, Elodie Baudoin, Joseph Murdaca, Claudine Moratal, Noura Lamghari, Giulia Chinetti, Jaap G. Neels, Anne-Sophie Rousseau
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
peroxisome-proliferator-activated receptor
fatty acid oxidation
doping control
regulatory T cells
inflammation
exercise
Online Access:https://www.mdpi.com/1422-0067/22/21/11497

Internet

https://www.mdpi.com/1422-0067/22/21/11497

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