Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

<p>Abstract</p> <p>Neurodegeneration, induced by misfolded tau protein, and neuroinflammation, driven by glial cells, represent the salient features of Alzheimer's disease (AD) and related human tauopathies. While tau neurodegeneration significantly correlates with disease pro...

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Bibliographic Details
Main Authors: Zilka Norbert, Kazmerova Zuzana, Jadhav Santosh, Neradil Peter, Madari Aladar, Obetkova Dominika, Bugos Ondrej, Novak Michal
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer's disease
Tauopathies
Neurofibrillary degeneration
Neuroinflammation
Microglia
Online Access:http://www.jneuroinflammation.com/content/9/1/47

Internet

http://www.jneuroinflammation.com/content/9/1/47

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