Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab–Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study

Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab–Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study

The combination of paclitaxel and ramucirumab is the second-line therapy of choice in the treatment of advanced gastric cancer. To date, no biomarkers are available in gastric cancer to predict the outcome of antiangiogenic therapy. The present prospective study included 35 patients undergoing secon...

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Bibliographic Details
Main Authors: Rosalba D’Alessandro, Maria Grazia Refolo, Annalisa Schirizzi, Giampiero De Leonardis, Rossella Donghia, Vito Guerra, Gianluigi Giannelli, Ivan Roberto Lolli, Maria Maddalena Laterza, Ferdinando De Vita, Caterina Messa, Claudio Lotesoriere
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
angiogenesis
gastric cancer
target therapy
biomarkers
cancer progression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.862116/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.862116/full

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