Aberrant Crypt Foci: The Case for Inclusion as a Biomarker for Colon Cancer

Aberrant crypt foci (ACF) are one of the earliest histopathological manifestations of colon cancer. In this review, we critically present the molecular, cellular, histopathological, and chemopreventive evidence that ACF are relevant biomarkers for colon cancer. The laboratory and clinical evidence a...

Full description

Bibliographic Details
Main Authors: Jay Morris, Michael J. Wargovich, Vondina R. Brown
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/2/3/1705/