Identification of a claudin-low subtype in clear cell renal cell carcinoma with implications for the evaluation of clinical outcomes and treatment efficacy

Identification of a claudin-low subtype in clear cell renal cell carcinoma with implications for the evaluation of clinical outcomes and treatment efficacy

BackgroundIn bladder and breast cancer, the claudin-low subtype is widely identified, revealing a distinct tumor microenvironment (TME) and immunological feature. Although we have previously identified individual claudin members as prognostic biomarkers in clear cell renal cell carcinoma (ccRCC), th...

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Bibliographic Details
Main Authors: Cuijian Zhang, Yifan Li, Jinqin Qian, Zhenpeng Zhu, Cong Huang, Zhisong He, Liqun Zhou, Yanqing Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
clear cell renal cell carcinoma (ccRCC)
claudin
tumor microenvironment
immunity
prognosis
immune checkpoint inhibitor (ICI)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020729/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020729/full

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