Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2

<p>Abstract</p> <p>Background</p> <p>The gene <it>CHEK2 </it>encodes a checkpoint kinase playing a key role in the DNA damage pathway. Though <it>CHEK2 </it>has been identified as an intermediate breast cancer susceptibility gene, only a small pr...

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Bibliographic Details
Main Authors: Sinilnikova Olga, McKay-Chopin Sandrine, Forey Nathalie, Michelon Jocelyne, Jordheim Lars P, Nguyen-Dumont Tú, Le Calvez-Kelm Florence, Southey Melissa C, Tavtigian Sean V, Lesueur Fabienne
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/4/39