ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation

ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation

Summary: LMNA gene mutation can cause muscular dystrophy, and post-translational modification plays a critical role in regulating its function. Here, we identify that lamin A is palmitoylated at cysteine 522, 588, and 591 residues, which are reversely catalyzed by palmitoyltransferase zinc finger DH...

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Bibliographic Details
Main Authors: Yuan Shen, Liang-Liang Zheng, Cai-Yun Fang, Yao-Yao Xu, Chao Wang, Jin-Tao Li, Ming-Zhu Lei, Miao Yin, Hao-Jie Lu, Qun-Ying Lei, Jia Qu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Stem cell research
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000482

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http://www.sciencedirect.com/science/article/pii/S2211124724000482

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