An Algorithm Framework for Drug-Induced Liver Injury Prediction Based on Genetic Algorithm and Ensemble Learning

An Algorithm Framework for Drug-Induced Liver Injury Prediction Based on Genetic Algorithm and Ensemble Learning

In the process of drug discovery, drug-induced liver injury (DILI) is still an active research field and is one of the most common and important issues in toxicity evaluation research. It directly leads to the high wear attrition of the drug. At present, there are a variety of computer algorithms ba...

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Bibliographic Details
Main Authors: Bowei Yan, Xiaona Ye, Jing Wang, Junshan Han, Lianlian Wu, Song He, Kunhong Liu, Xiaochen Bo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
DILI
genetic algorithm
ensemble learning
PCA/MCA
QSAR
molecular representation
Online Access:https://www.mdpi.com/1420-3049/27/10/3112

Internet

https://www.mdpi.com/1420-3049/27/10/3112

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