Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates

Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates

Abstract Background Red blood cell invasion by the Plasmodium vivax merozoite requires interaction between the Duffy antigen receptor for chemokines (DARC) and the P. vivax Duffy-binding protein II (PvDBPII). Given that the disruption of this interaction prevents P. vivax blood-stage infection, a Pv...

Full description

Bibliographic Details
Main Authors: Lemu Golassa, Alebachew Messele, Eniyou Cheryll Oriero, Alfred Amambua-Ngwa
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Malaria Journal
Subjects:
Plasmodium vivax
PvDBPII
DARC
Polymorphism
Mutations
Online Access:https://doi.org/10.1186/s12936-021-03843-7

Internet

https://doi.org/10.1186/s12936-021-03843-7

Similar Items