An Improved Synthesis of 4-Chlorocoumarin-3-sulfonyl Chloride and Its Reactions with Different Bidentate Nucleophiles to Give Pyrido[1',2':2,3]- and Thiazino[3',2':2,3]-1,2,4-Thiadiazino[6,5-c]Benzopyran-6-one 7,7-Dioxides

An Improved Synthesis of 4-Chlorocoumarin-3-sulfonyl Chloride and Its Reactions with Different Bidentate Nucleophiles to Give Pyrido[1',2':2,3]- and Thiazino[3',2':2,3]-1,2,4-Thiadiazino[6,5-c]Benzopyran-6-one 7,7-Dioxides

An improved synthetic method affording 4-chlorocoumarin-3-sulfonyl chloride (4) in very good yield (ca. 85 %) is reported. This compound was reacted with various bidentate nucleophiles such as 2-aminopyridines and 2-aminothiazoles in order to obtain substituted pyrido- and thiazino-1,2,4-thiadiazino...

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Bibliographic Details
Main Authors: Emil Popovski, Gerald Draeger, Bozhana Mikhova, Evamarie Hey-Hawkins, Ahmed Jashari
Format: Article
Language:English
Published: MDPI AG 2007-08-01
Series:Molecules
Subjects:
Synthesis
coumarin
1
2
4-thiadiazines
fused heterocycles.
Online Access:http://www.mdpi.com/1420-3049/12/8/2017/

Internet

http://www.mdpi.com/1420-3049/12/8/2017/

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