YAP Activation and Implications in Patients and a Mouse Model of Biliary Atresia

YAP Activation and Implications in Patients and a Mouse Model of Biliary Atresia

Background and Aim: Biliary atresia (BA), an inflammatory destruction of the bile ducts, leads to liver fibrosis in infants and accounts for half of cases undergoing pediatric liver transplantation. Yes-associated protein (YAP), an effector of the Hippo signaling pathway, is critical in maintaining...

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Bibliographic Details
Main Authors: Chao Zheng, Jiaqian Luo, Yifan Yang, Rui Dong, Fa-Xing Yu, Shan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pediatrics
Subjects:
Biliary Atresia
yes-associated protein
hippo signaling pathway
liver fibrosis
Recombinant Ankyrin Repeat Domain Protein 1
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2020.618226/full

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https://www.frontiersin.org/articles/10.3389/fped.2020.618226/full

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