Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics

Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics

Background: Ovarian cancer, colloquially termed the “silent killer” among gynecological malignancies, remains elusive due to its often-asymptomatic progression and diagnostic challenges. Central to its pathogenesis is the overactive PI3K/Akt/mTOR signaling pathway, responsible for various cellular f...

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Bibliographic Details
Main Authors: Hanan M. Alharbi, Taha Alqahtani, Ali H. Alamri, Vinoth Kumarasamy, Vetriselvan Subramaniyan, K. Suresh Babu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
ovarian cancer therapeutics
therapeutic efficacy
mangiferin
curcumin
PI3K/Akt/mTOR pathway
synergistic interplay
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1276209/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1276209/full

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