Perturbing the Hypothalamic–Pituitary–Adrenal Axis: A Mathematical Model for Interpreting PTSD Assessment Tests

Perturbing the Hypothalamic–Pituitary–Adrenal Axis: A Mathematical Model for Interpreting PTSD Assessment Tests

We use a dynamical systems model of the hypothalamic–pituitary–adrenal (HPA) axis to understand the mechanisms underlying clinical protocols used to probe patient stress response. Specifically, we address dexamethasone (DEX) and ACTH challenge tests, which probe pituitary and adrenal gland responses...

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Bibliographic Details
Main Authors: Lae Un Kim, Maria R. D’Orsogna, Tom Chou
Format: Article
Language:English
Published: Ubiquity Press 2018-02-01
Series:Computational Psychiatry
Subjects:
hpa axis
ptsd
cortisol
dex suppression test
acth challenge test
Online Access:https://cpsyjournal.org/articles/39

Internet

https://cpsyjournal.org/articles/39

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