Novel Cell Permeable Polymers of <i>N</i>-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids

Novel Cell Permeable Polymers of <i>N</i>-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids

The present study aimed to synthesize novel polycationic polymers composed of <i>N</i>-substituted L-2,3-diaminopropionic acid residues (DAPEGs) and investigate their cell permeability, cytotoxicity, and DNA-binding ability. The most efficient cell membrane-penetrating compounds (O2Oc-Da...

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Bibliographic Details
Main Authors: Anita Romanowska, Katarzyna Węgrzyn, Katarzyna Bury, Emilia Sikorska, Aleksandra Gnatek, Agnieszka Piwkowska, Igor Konieczny, Adam Lesner, Magdalena Wysocka
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
polymers
peptidomimetics
AFM
transfection
molecular modelling
Online Access:https://www.mdpi.com/1422-0067/22/5/2571

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https://www.mdpi.com/1422-0067/22/5/2571

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