The Chikungunya Virus Capsid Protein Contains Linear B Cell Epitopes in the N- and C-Terminal Regions that are Dependent on an Intact C-Terminus for Antibody Recognition

The Chikungunya Virus Capsid Protein Contains Linear B Cell Epitopes in the N- and C-Terminal Regions that are Dependent on an Intact C-Terminus for Antibody Recognition

Chikungunya virus (CHIKV) is an arthropod-borne agent that causes severe arthritic disease in humans and is considered a serious health threat in areas where competent mosquito vectors are prevalent. CHIKV has recently been responsible for several millions of cases of disease, involving over 40 coun...

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Bibliographic Details
Main Authors: Lucas Y. H. Goh, Jody Hobson-Peters, Natalie A. Prow, Kelly Baker, Thisun B. H. Piyasena, Carmel T. Taylor, Ashok Rana, Marcus L. Hastie, Jeff J. Gorman, Roy A. Hall
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Viruses
Subjects:
chikungunya virus
monoclonal antibodies
capsid protein
epitope mapping
linear B cell epitope
C-terminus
N-terminus
Online Access:http://www.mdpi.com/1999-4915/7/6/2754

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http://www.mdpi.com/1999-4915/7/6/2754

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