Ruthenium-Based Catalytic Systems Incorporating a Labile Cyclooctadiene Ligand with N-Heterocyclic Carbene Precursors for the Atom-Economic Alcohol Amidation Using Amines

Ruthenium-Based Catalytic Systems Incorporating a Labile Cyclooctadiene Ligand with N-Heterocyclic Carbene Precursors for the Atom-Economic Alcohol Amidation Using Amines

Transition-metal-catalyzed amide-bond formation from alcohols and amines is an atom-economic and eco-friendly route. Herein, we identified a highly active in situ N-heterocyclic carbene (NHC)/ruthenium (Ru) catalytic system for this amide synthesis. Various substrates, including sterically hindered...

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Bibliographic Details
Main Authors: Cheng Chen, Yang Miao, Kimmy De Winter, Hua-Jing Wang, Patrick Demeyere, Ye Yuan, Francis Verpoort
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
ruthenium (Ru)
N-heterocyclic carbenes (NHCs)
homogeneous catalysis
in situ
amide bonds
synthesis
Online Access:http://www.mdpi.com/1420-3049/23/10/2413

Internet

http://www.mdpi.com/1420-3049/23/10/2413

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