DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy

DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy

Conventional antineoplastic therapies cause severe normal tissue damage and existing cytoprotectants with acute toxicities or potential tumor protection limit their clinical application. We evaluated the selective cytoprotection of 2,2-dimethylthiazolidine hydrochloride in this study, which could pr...

Full description

Bibliographic Details
Main Authors: Yuwei Yang, Yuanfang Chen, Haikang Tang, Ziqi Zhang, Xiaoliang Zhou, Wenqing Xu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Chemotherapy
Cytoprotectant
Ferroptosis
Mitochondria
Radiotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224001082

Internet

http://www.sciencedirect.com/science/article/pii/S0753332224001082

Similar Items