The role of DPO-1 and XE991-sensitive potassium channels in perivascular adipose tissue-mediated regulation of vascular tone

The role of DPO-1 and XE991-sensitive potassium channels in perivascular adipose tissue-mediated regulation of vascular tone

The anti-contractile effect of perivascular adipose tissue (PVAT) is an important mechanism in the modulation of vascular tone in peripheral arteries. Recent evidence has implicated the XE991-sensitive voltage-gated Kv (KCNQ) channels in the regulation of arterial tone by PVAT. However, until now th...

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Bibliographic Details
Main Authors: Dmitry Tsvetkov, Jean-Yves Tano, Mario Kassmann, Ning Wang, Rudolf Schubert, Maik Gollasch
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Physiology
Subjects:
XE991
BK channels
KCNQ channels
Kv1.5 channels
adipocyte-derived relaxing factor (ADRF)
perivascular adipose tissue (PVAT)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00335/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00335/full

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