Human organ donor-derived vagus nerve biopsies allow for well-preserved ultrastructure and high-resolution mapping of myelinated and unmyelinated fibers

Human organ donor-derived vagus nerve biopsies allow for well-preserved ultrastructure and high-resolution mapping of myelinated and unmyelinated fibers

Abstract The vagus nerve provides motor, sensory, and autonomic innervation of multiple organs, and electrical vagus nerve stimulation (VNS) provides an adjunctive treatment option for e.g. medication-refractory epilepsy and treatment-resistant depression. The mechanisms of action for VNS are not kn...

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Bibliographic Details
Main Authors: Leif A. Havton, Natalia P. Biscola, Esther Stern, Plamen V. Mihaylov, Chandrashekhar A. Kubal, John M. Wo, Anita Gupta, Elizabeth Baronowsky, Matthew P. Ward, Deborah M. Jaffey, Terry L. Powley
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03248-1

Internet

https://doi.org/10.1038/s41598-021-03248-1

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