Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced Alzheimer's disease in rats

Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced Alzheimer's disease in rats

Background/Aim: Gallic acid and metformin are plant-derived compounds with biological effects. The present study aimed to evaluate the protective effect of gallic acid and hesperidin against aluminium chloride (AlCl3)-induced Alzheimer's disease in Wistar rats. Methods: Thirty-five male rats we...

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Bibliographic Details
Main Authors: Bidemi Emmanuel Ekundayo, Tajudeen Olabisi Obafemi, Blessing Ariyo Afolabi, Olusola Bolaji Adewale, Amos Onasanya, Olukemi Adetutu Osukoya, John Adeolu Falode, Christopher Akintayo, Isaac Adekola Adu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Hesperidin
Gallic acid
Alzheimer's disease
Neuroprotective
Cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S266714252200152X

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http://www.sciencedirect.com/science/article/pii/S266714252200152X

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