Heparanase Levels Are Elevated in the Plasma of Pediatric Cancer Patients and Correlate with Response to Anticancer Treatment

Heparanase Levels Are Elevated in the Plasma of Pediatric Cancer Patients and Correlate with Response to Anticancer Treatment

Heparanase is an endoglycosidase that specifically cleaves heparan sulfate (HS) side chains of heparan sulfate proteoglycans, the major proteoglycan in the extracellular matrix (ECM) and cell surfaces. Heparanase upregulation was documented in an increasing number of primary human tumors, correlatin...

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Bibliographic Details
Main Authors: Itay Shafat, Ayelet Ben Barak, Sergey Postovsky, Ronit Elhasid, Neta Ilan, Israel Vlodavsky, Miriam Weyl Ben Arush
Format: Article
Language:English
Published: Elsevier 2007-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Heparanase
ELISA
marker
anticancer treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800194

Internet

http://www.sciencedirect.com/science/article/pii/S1476558607800194

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