Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection.

Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection.

BACKGROUND:Congenital cytomegalovirus infection can lead to severe sequelae. When fetal infection is confirmed, we hypothesize that fetal treatment could improve the outcome. Maternal oral administration of an effective drug crossing the placenta could allow fetal treatment. Letermovir (LMV) and Mar...

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Bibliografski detalji
Glavni autori: Valentine Faure Bardon, Gilles Peytavin, Minh Patrick Lê, Tiffany Guilleminot, Elisabeth Elefant, Julien Stirnemann, Marianne Leruez-Ville, Yves Ville
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2020-01-01
Serija:PLoS ONE
Online pristup:https://doi.org/10.1371/journal.pone.0232140

Internet

https://doi.org/10.1371/journal.pone.0232140

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