Therapeutic drug monitoring of sertraline in children and adolescents: A naturalistic study with insights into the clinical response and treatment of obsessive-compulsive disorder

Therapeutic drug monitoring of sertraline in children and adolescents: A naturalistic study with insights into the clinical response and treatment of obsessive-compulsive disorder

Background: Sertraline is a selective serotonin reuptake inhibitor with specific indications in child and adolescent psychiatry. Notwithstanding its frequent use and clinical benefits, the relationship between pharmacokinetics, pharmacodynamics, efficacy, and tolerability of sertraline across indica...

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Main Authors: Elvira Tini, Lukasz Smigielski, Marcel Romanos, Christoph Wewetzer, Andreas Karwautz, Karl Reitzle, Christoph U. Correll, Paul L. Plener, Uwe Malzahn, Peter Heuschmann, Stefan Unterecker, Maike Scherf-Clavel, Hans Rock, Gisela Antony, Wolfgang Briegel, Christian Fleischhaker, Tobias Banaschewski, Tobias Hellenschmidt, Hartmut Imgart, Michael Kaess, Michael Kölch, Tobias Renner, Su-Yin Reuter-Dang, Christian Rexroth, Gerd Schulte-Körne, Frank Theisen, Stefanie Fekete, Regina Taurines, Manfred Gerlach, Karin Maria Egberts, Susanne Walitza
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Comprehensive Psychiatry
Subjects:
TDM
antidepressants
selective serotonin reuptake inhibitors
pharmacovigilance
steady state concentration
Online Access:http://www.sciencedirect.com/science/article/pii/S0010440X22000074

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http://www.sciencedirect.com/science/article/pii/S0010440X22000074

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