Coupling between the Basic Replicon and the Kis-Kid Maintenance System of Plasmid R1: Modulation by Kis Antitoxin Levels and Involvement in Control of Plasmid Replication

Coupling between the Basic Replicon and the Kis-Kid Maintenance System of Plasmid R1: Modulation by Kis Antitoxin Levels and Involvement in Control of Plasmid Replication

kis-kid, the auxiliary maintenance system of plasmid R1 and copB, the auxiliary copy number control gene of this plasmid, contribute to increase plasmid replication efficiency in cells with lower than average copy number. It is thought that Kis antitoxin levels decrease in these cells and that this...

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Bibliographic Details
Main Authors: Juan López-Villarejo, Damián Lobato-Márquez, Ramón Díaz-Orejas
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Toxins
Subjects:
plasmid R1
plasmid replication and copy number control
parD (kis-kid) antitoxin-toxin system
Kis antitoxin
ClpAP protease
transcriptional regulation
CopB repressor
coupling plasmid maintenance systems
Online Access:http://www.mdpi.com/2072-6651/7/2/478

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http://www.mdpi.com/2072-6651/7/2/478

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