Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma

Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma

Despite the numerous research studies on traumatic brain injury (TBI), many physiopathologic mechanisms remain unknown. TBI is a complex process, in which neuroinflammation and glial cells play an important role in exerting a functional immune and damage-repair response. The activation of the NLRP3...

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Bibliographic Details
Main Authors: Ana Belen Lopez-Rodriguez, Céline Decouty-Perez, Victor Farré-Alins, Alejandra Palomino-Antolín, Paloma Narros-Fernández, Javier Egea
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
traumatic brain injury
inflammasome
NLRP3
neuroinflammation
microglia
astrocytes
Online Access:https://www.mdpi.com/1999-4923/14/8/1550

Internet

https://www.mdpi.com/1999-4923/14/8/1550

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