Pro-inflammatory Stimulation of Monocytes by ANCA Is Linked to Changes in Cellular Metabolism

Pro-inflammatory Stimulation of Monocytes by ANCA Is Linked to Changes in Cellular Metabolism

Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively investigated, the function of monocytes remains relativ...

Full description

Bibliographic Details
Main Authors: Eóin C. O'Brien, Carla A. White, Jason Wyse, Emma Leacy, Richard K. Porter, Mark A. Little, Fionnuala B. Hickey
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Medicine
Subjects:
ANCA vasculitis
monocyte
immunometabolism
autoimmune
metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00553/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00553/full

Similar Items