Identification of Potential Non-Systemic Therapeutics for Hyperammonemia

A non-absorbable therapeutic candidate for the treatment of hyperammonemia has been identified and characterized. Conventional approaches to reducing ammonia concentration in the blood and colon include acidifying the colon, inhibiting the bacterial production of ammonia, and activation of the urea...

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Bibliographic Details
Main Authors: Brad Nicklas, Simon Velasquez Morales, Jian Qian, Kyle J. Stephens, David R. Corbin, Mark B. Shiflett, Cory J. Berkland, Alan M. Allgeier
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Drugs and Drug Candidates
Subjects:
Online Access:https://www.mdpi.com/2813-2998/2/4/40