Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

<p>Abstract</p> <p>Background</p> <p>The abnormal accumulation of amyloid-beta peptide is believed to cause malfunctioning of neurons in the Alzheimer's disease brain. Amyloid-beta exists in different assembly forms in the aging mammalian brain including monomers,...

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Bibliographic Details
Main Authors: O'Connor Peter B, Zhao Cheng, Yamin Rina, McKee Ann C, Abraham Carmela R
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/4/1/33