Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment

Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment

Abstract Background Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevelopmental outcomes are more frequent and/or more severe when toxic expos...

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Bibliographic Details
Main Authors: Zhaoxi Wang, Birgit Claus Henn, Chaolong Wang, Yongyue Wei, Li Su, Ryan Sun, Han Chen, Peter J. Wagner, Quan Lu, Xihong Lin, Robert Wright, David Bellinger, Molly Kile, Maitreyi Mazumdar, Martha Maria Tellez-Rojo, Lourdes Schnaas, David C. Christiani
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Environmental Health
Subjects:
Genome-wide association study
Gene-environment interactions
Child development
Lead poisoning
Single nucleotide polymorphism
UNC5D
Online Access:http://link.springer.com/article/10.1186/s12940-017-0288-3

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http://link.springer.com/article/10.1186/s12940-017-0288-3

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