Circulating metabolome landscape in Lynch syndrome

Circulating metabolome landscape in Lynch syndrome

Abstract Circulating metabolites systemically reflect cellular processes and can modulate the tissue microenvironment in complex ways, potentially impacting cancer initiation processes. Genetic background increases cancer risk in individuals with Lynch syndrome; however, not all carriers develop can...

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Bibliographic Details
Main Authors: Tiina A. Jokela, Jari E. Karppinen, Minta Kärkkäinen, Jukka-Pekka Mecklin, Simon Walker, Toni T. Seppälä, Eija K. Laakkonen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cancer & Metabolism
Subjects:
Metabolomic biomarkers
DNA mismatch repair deficiency
Hereditary cancer
Lipid metabolism
Cholesterol metabolism
Circulating amino acids
Online Access:https://doi.org/10.1186/s40170-024-00331-9

Internet

https://doi.org/10.1186/s40170-024-00331-9

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