Early Endosomal Vps34-Derived Phosphatidylinositol-3-Phosphate Is Indispensable for the Biogenesis of the Endosomal Recycling Compartment

Early Endosomal Vps34-Derived Phosphatidylinositol-3-Phosphate Is Indispensable for the Biogenesis of the Endosomal Recycling Compartment

Phosphatidylinositol-3-phosphate (PI3P), a major identity tag of early endosomes (EEs), provides a platform for the recruitment of numerous cellular proteins containing an FYVE or PX domain that is required for PI3P-dependent maturation of EEs. Most of the PI3P in EEs is generated by the activity of...

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Bibliographic Details
Main Authors: Marina Marcelić, Hana Mahmutefendić Lučin, Antonija Jurak Begonja, Gordana Blagojević Zagorac, Pero Lučin
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
phosphatidylinositol-3-phosphate
Vps34
VPS34-IN1
Rab11a endosomes
endosomal recycling compartment
Online Access:https://www.mdpi.com/2073-4409/11/6/962

Internet

https://www.mdpi.com/2073-4409/11/6/962

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