Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells.

Discs large homolog 5 (Dlg5) is a member of the membrane-associated guanylate kinase adaptor family of proteins, some of which are involved in the regulation of epithelial-to-mesenchymal transition (EMT). Dlg5 has been described as a susceptibility gene for Crohn's disease; however, the physiol...

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Main Authors: Takuhito Sezaki, Kohki Inada, Takayuki Sogabe, Kumiyo Kakuda, Lucia Tomiyama, Yohsuke Matsuno, Takafumi Ichikawa, Michinori Matsuo, Kazumitsu Ueda, Noriyuki Kioka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335148?pdf=render