Depletion of lncRNA MEG3 Ameliorates Imatinib-Induced Injury of Cardiomyocytes via Regulating miR-129-5p/HMGB1 Axis

Imatinib is a classical targeted drug to treat chronic myeloid leukemia (CML). However, it shows cardiotoxicity, which limits its clinical application. Long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) shows proapoptotic properties in human cells. This study is performed to investigate...

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Bibliographic Details
Main Authors: Peng Tang, Jinjian Zhou, Huagang Liu, Shenglan Mei, Kai Wang, Hao Ming
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2023/1108280