Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial.

Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial.

<h4>Background</h4>Current artesunate (ARS) regimens for severe malaria are complex. Once daily intramuscular (i.m.) injection for 3 d would be simpler and more appropriate for remote health facilities than the current WHO-recommended regimen of five intravenous (i.v.) or i.m. injections...

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Main Authors: Peter G Kremsner, Akim A Adegnika, Aurore B Hounkpatin, Jeannot F Zinsou, Terrie E Taylor, Yamikani Chimalizeni, Alice Liomba, Maryvonne Kombila, Marielle K Bouyou-Akotet, Denise P Mawili Mboumba, Tsiri Agbenyega, Daniel Ansong, Justice Sylverken, Bernhards R Ogutu, Godfrey A Otieno, Anne Wangwe, Kalifa A Bojang, Uduak Okomo, Frank Sanya-Isijola, Charles R Newton, Patricia Njuguna, Michael Kazungu, Reinhold Kerb, Mirjam Geditz, Matthias Schwab, Thirumalaisamy P Velavan, Christian Nguetse, Carsten Köhler, Saadou Issifou, Stefanie Bolte, Thomas Engleitner, Benjamin Mordmüller, Sanjeev Krishna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001938

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https://doi.org/10.1371/journal.pmed.1001938

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