Proteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy

Proteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy

BackgroundNeoadjuvant radiotherapy (neo-RT) is widely used in locally advanced rectal cancer (LARC) as a component of radical treatment. Despite the advantages of neo-RT, which typically improves outcomes in LARC patients, the lack of reliable biomarkers that predict response and monitor the efficac...

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Bibliographic Details
Main Authors: Anna Wojakowska, Lukasz Marczak, Marcin Zeman, Mykola Chekan, Ewa Zembala-Nożyńska, Krzysztof Polanski, Aleksander Strugała, Piotr Widlak, Monika Pietrowska
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
rectal cancer
radiotherapy
tissue
metabolomics
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1323961/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1323961/full

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