Dendritic Cells or Macrophages? The Microenvironment of Human Clear Cell Renal Cell Carcinoma Imprints a Mosaic Myeloid Subtype Associated with Patient Survival

Dendritic Cells or Macrophages? The Microenvironment of Human Clear Cell Renal Cell Carcinoma Imprints a Mosaic Myeloid Subtype Associated with Patient Survival

Since their initial description by Elie Metchnikoff, phagocytes have sparked interest in a variety of biologic disciplines. These important cells perform central functions in tissue repair and immune activation as well as tolerance. Myeloid cells can be immunoinhibitory, particularly in the tumor mi...

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Bibliographic Details
Main Authors: Dorothee Brech, Anna S. Herbstritt, Sarah Diederich, Tobias Straub, Evangelos Kokolakis, Martin Irmler, Johannes Beckers, Florian A. Büttner, Elke Schaeffeler, Stefan Winter, Matthias Schwab, Peter J. Nelson, Elfriede Noessner
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
mononuclear phagocyte system
macrophage plasticity
tissue macrophage
tumor microenvironment
gene expression
VSIG4
Online Access:https://www.mdpi.com/2073-4409/11/20/3289

Internet

https://www.mdpi.com/2073-4409/11/20/3289

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