Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

Abstract Background Human induced pluripotent stem cells (iPSC) have opened new avenues for regenerative medicine. Consequently, iPSC-derived motor neurons have emerged as potentially viable therapies for spinal cord injuries and neurodegenerative disorders including Amyotrophic Lateral Sclerosis. H...

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Bibliographic Details
Main Authors: Emilia Solomon, Katie Davis-Anderson, Blake Hovde, Sofiya Micheva-Viteva, Jennifer Foster Harris, Scott Twary, Rashi Iyer
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Molecular and Cell Biology
Subjects:
iPSCs
Motor neurons
Stem cell reprogramming
Transcriptomics
Neuronal development
In vitro neuronal networks
Online Access:https://doi.org/10.1186/s12860-021-00343-z

Internet

https://doi.org/10.1186/s12860-021-00343-z

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