Poly[ADP-ribose] polymerase-1 expression is related to cold ischemia, acute tubular necrosis, and delayed renal function in kidney transplantation.

UNLABELLED:Cold ischemia time especially impacts on outcomes of expanded-criteria donor (ECD) transplantation. Ischemia-reperfusion (IR) injury produces excessive poly[ADP-Ribose] Polymerase-1 (PARP-1) activation. The present study explored the hypothesis that increased tubular expression of PARP-1...

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Main Authors: Francisco O'Valle, Raimundo G M Del Moral, María del Carmén Benítez, David Martín-Oliva, Mercedes Gómez-Morales, David Aguilar, José Aneiros-Fernández, Pedro Hernández-Cortés, Antonio Osuna, Francesc Moreso, Daniel Serón, Francisco J Oliver, Raimundo G Del Moral
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2745752?pdf=render