Targeting HSP47 and HSP70: promising therapeutic approaches in liver fibrosis management

Abstract Liver fibrosis is a liver disease in which there is an excessive buildup of extracellular matrix proteins, including collagen. By regulating cytokine production and the inflammatory response, heat shock proteins (HSPs) contribute significantly to a wider spectrum of fibrotic illnesses, such...

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Bibliographic Details
Main Authors: Eslam E. Abd El-Fattah, Amr Y. Zakaria
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-022-03759-z